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Parkinson’s disease is one of the most studied medical conditions. It’s both complex and debilitating, which is why ongoing research for a cure is a priority in the medical community. The volunteers at Connecticut Advocates for Parkinson’s in Windsor, CT, are committed to helping the cause and are excited to share new findings that may take researchers one step closer to a cure.

A primary cause of Parkinson’s is that brain cells begin to die, specifically in the brainstem and those that produce dopamine. Discovering the cause of cell death is a crucial part of forward progress, and the results of a new study have found a potential link. Conducted by Newcastle University and the University of Sussex in the United Kingdom, this new study, titled “Mitochondrial DNA changes in pedunculopontine cholinergic neurons in Parkinson disease,” focused on identifying changes in the mitochondrial DNA in the brainstem.

parkinsons-connecticut-advocates-for-parkinsonsThe research was specific to the pedunculopontine nucleus and how changes in mitochondrial DNA affected cell death. Mitochondria produce and store energy within cells. As these cells die, new findings showed that cholinergic neurons, which help send signals between neurons in the brain stem, become unable to communicate. This leads to many of the side effects of Parkinson’s disease, such as difficulty with walking and posture.

A key part of developing a Parkinson’s cure is identifying which cells need to be targeted in treatment. By recognizing changes in the mitochondrial DNA and pedunculopontine nucleus cholinergic neurons, researchers can direct new research at better understanding their role in Parkinson’s and how targeted treatment can lead to better disease management and possibly a cure.

It’s important to continue supporting Parkinson’s research to improve the lives of people who have it. If you or a loved one are dealing with this disease, turn to Connecticut Advocates for Parkinson’s. As the go-to resource for patients, they provide support and assistance through a wide variety of services. Call (860) 266-6040 to speak with a volunteer and visit their website and Facebook to learn more.

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